2022 - hFOB 1.19 Growth trends and future research

As science evolves, humanity learns to overcome imperfections in this world. One of the many flaws that we face as humans is bodily defects such as osteoporosis. The integrity and rigidity of our bones comes from a chemical component called calcium phosphate (Ca3 (PO4)2). Thanks to the advancements in 3D printing technology, it is possible to print calcium phosphate structures that provide a strong representation of hard bone. Hard bone is not the only part of the bone that is vital to its functions. Bone marrow is required in bones to create the necessary cells the body needs. In the circulatory system. hFOB 1.19 is an osteoblast cell line that has, under observation, been proven to create tissues similar to adult bone marrow. With these findings, we want to observe the growth of hFOB 1.19 on 3D printed surfaces. The growing surfaces proposed are the aforementioned calcium phosphate, calcium carbonate, and a specialized Biolnk meant for cell culture. After observation of the cells and their growth patterns, we will build different types of scaffolds for the cells to grow in vitro. With the growth data of the cells received from these tests, we will be able to further refine the design and shape of the 3D printed material and the optimal growth for the hFOB 1.19. When the results are attained from these tests, a conclusion will be added to this abstract and display the growth capabilities of hFOB 1.19 on 3D Printed Materials. In the meantime, the data that we have collected shows a strong correlation between hFOB 1.19 and its viability on 3D Printed Calcium Phosphate Structures. With this, there is a possibility for a future with bone replacement and repair surgeries to be accomplished with 3D Printed Bones.